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La Nopalera Mexican Restaurant San Marco

About Us

La Nopalera Mexican Restaurant – San Marco, located in the heart of Jacksonville, FL, has been proudly serving Duval and St. John's counties since 1996. Known for our vibrant atmosphere and authentic Mexican cuisine, we offer a flavorful menu featuring tacos, burritos, sizzling fajitas, fresh guacamole, and handcrafted margaritas. Join us for happy hour specials, live music, and outdoor patio seating perfect for any occasion. Whether you're dining with friends, enjoying a family meal, or celebrating something special, La Nopalera is your go-to destination for bold flavors and great vibes. Call us at 904-399-1768 to place an order or make a reservation today!


Areas Served

Jacksonville, FL | Downtown | Riverside, Jacksonville, FL | San Marco, Jacksonville, FL | Baymeadows, Jacksonville, FL | Arlington, Jacksonville, FL | San Jose, Jacksonville, FL | Duval County, FL | St. Johns County, FL

Languages Spoken


What We Offer

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Testimonials

On 9/20/2025 Steve E. had this to say:
Great food and always friendly service. This location has lived up to the standards of La Nopalera

On 9/8/2025 Chris Carter had this to say:
Best tasting carnitas in Jax! Bar none! Will always be back to la nop! Great atmosphere 👌

On 9/1/2025 franklin phan had this to say:
Good portions

On 8/27/2025 Melissa B. had this to say:
We come to La Nopalera at least every other week, and honestly, I'm always surprised to see some of the negative reviews. This spot is one of our go-tos! The fajitas are my favorite thing on menu- they're absolutely delicious. The portions are huge, the flavor is great, and you really can't beat the value for the money. My husband almost always orders the shrimp and steak dish, and it's consistently good--tender steak, flavorful shrimp, and plenty to fill you up. The prices here are extremely fair for how much food you get, and we've never left hungry. For the quality and the portion sizes, it's one of the best values around. Bottom line: La Nopalera is a staple for us, and we'll keep coming back again and again.

On 8/26/2025 Shatavia Eady had this to say:
The food is soo good. I came here for lunch. I had a quesadilia with steak. It was delicious.


Contact Us

La Nopalera Mexican Restaurant San Marco
1434 Hendricks Ave Jacksonville, FL 32207
Phone: (904) 399-1768
Email: nelleon22@yahoo.com

Next to the rail road in San Marco,
Behind Panera Bread

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Payment Types Accepted

Visa, MasterCard, American Express, Discover, Debit Cards, Cash, Apple Pay, Android Pay

Our Hours

Holiday Hours May Vary. Please Call For Details.

Monday: 11:00 AM - 10:00 PM
Tuesday: 11:00 AM - 10:00 PM
Wednesday: 11:00 AM - 10:00 PM
Thursday: 11:00 AM - 10:00 PM
Friday: 11:00 AM - 11:00 PM
Saturday: 11:30 AM - 11:00 PM
Sunday: 11:30 AM - 9:30 PM


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